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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDPK1
All Species:
15.15
Human Site:
S421
Identified Species:
27.78
UniProt:
O15530
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15530
NP_002604.1
556
63152
S421
Q
Y
I
H
D
L
D
S
N
S
F
E
L
D
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537000
560
63701
T425
Q
Y
I
H
D
L
D
T
N
S
F
E
L
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2A0
559
63740
T424
Q
Y
I
H
D
L
D
T
N
S
F
E
L
D
L
Rat
Rattus norvegicus
O55173
559
63591
T424
Q
Y
I
H
D
L
D
T
N
S
F
E
L
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518589
320
36424
L222
K
D
L
V
E
K
L
L
V
L
D
S
T
K
R
Chicken
Gallus gallus
Q6U1I9
432
48872
Q334
H
L
L
E
G
L
L
Q
K
D
R
T
K
R
L
Frog
Xenopus laevis
Q6GPN6
434
49096
Q336
N
L
L
E
G
L
L
Q
K
D
R
T
K
R
I
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
Q335
H
L
L
E
G
L
L
Q
K
D
R
T
K
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W0V1
836
94060
D650
K
N
S
F
D
L
N
D
A
E
K
L
Q
R
L
Honey Bee
Apis mellifera
XP_394208
537
61368
E417
I
A
D
L
S
P
E
E
I
R
N
R
L
E
K
Nematode Worm
Caenorhab. elegans
Q9Y1J3
636
71898
S449
E
I
A
P
R
A
N
S
E
A
E
K
N
R
A
Sea Urchin
Strong. purpuratus
XP_786576
539
61612
R426
T
P
A
E
R
K
Q
R
L
E
R
Q
G
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12236
1081
121642
A879
F
G
R
F
L
V
F
A
K
R
R
Q
P
N
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
93.3
N.A.
94.8
95.3
N.A.
52.1
28.6
28
27.5
N.A.
32.5
54.1
32.5
58
Protein Similarity:
100
N.A.
N.A.
95
N.A.
96.2
96.4
N.A.
54.6
44
43.8
43.3
N.A.
44.1
66.1
52.2
70.3
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
93.3
93.3
N.A.
0
13.3
6.6
13.3
N.A.
20
6.6
6.6
0
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
20
20
20
20
N.A.
33.3
20
33.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
16
0
0
8
0
8
8
8
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
39
0
31
8
0
24
8
0
0
31
0
% D
% Glu:
8
0
0
31
8
0
8
8
8
16
8
31
0
8
8
% E
% Phe:
8
0
0
16
0
0
8
0
0
0
31
0
0
0
0
% F
% Gly:
0
8
0
0
24
0
0
0
0
0
0
0
8
0
0
% G
% His:
16
0
0
31
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
31
0
0
0
0
0
8
0
0
0
0
0
8
% I
% Lys:
16
0
0
0
0
16
0
0
31
0
8
8
24
16
8
% K
% Leu:
0
24
31
8
8
62
31
8
8
8
0
8
39
0
54
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
0
0
0
0
16
0
31
0
8
0
8
8
0
% N
% Pro:
0
8
0
8
0
8
0
0
0
0
0
0
8
0
8
% P
% Gln:
31
0
0
0
0
0
8
24
0
0
0
16
8
0
0
% Q
% Arg:
0
0
8
0
16
0
0
8
0
16
39
8
0
39
8
% R
% Ser:
0
0
8
0
8
0
0
16
0
31
0
8
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
24
0
0
0
24
8
0
0
% T
% Val:
0
0
0
8
0
8
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
31
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _